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池田研究室|熊本大学ヒトレトロウイルス学共同研究センター 分子ウイルス・遺伝学分野
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池田研究室|熊本大学ヒトレトロウイルス学共同研究センター 分子ウイルス・遺伝学分野
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  • A patient infected with SARS-CoV-2 over 100 days
  • Resistance of SARS-CoV-2 variants to neutralization by antibodies induced in convalescent patients with COVID-19. Cell Rep. 36, 109385, 2021.
  • SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity. Cell Host Microbe. 29, 1124-1136.e11, 2021.
  • A role for gorilla APOBEC3G in shaping lentivirus evolution including transmission to humans. PLoS Pathog, 16, e1008812. 2020.
  • Evolved Proteins Inhibit Entry of Enfuvirtide-Resistant HIV-1. ACS Infect Dis. 5, 634-640. 2019.
  • HIV-1 Vif triggers cell cycle arrest by degrading cellular PPP2R5 phospho-regulators. Cell Rep. 29, 1057-1065.e4. 2019.
  • HIV-1 restriction by endogenous APOBEC3G in the myeloid cell line THP-1. J Gen Virol. 100, 1140-1152. 2019.
  • Evaluation of sequence variability in HIV-1 gp41 C-peptide helix-grafted proteins. Bioorg Med Chem. 26, 1220-1224. 2018.
  • Natural APOBEC3C variants can elicit differential HIV-1 restriction activity. Retrovirology. 15, 78. 2018.
  • HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G. PLoS Pathog. 14, e1007010. 2018.
  • Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 protease. Nat Commun. 9, 4137. 2018.
  • Opossum APOBEC1 is a DNA mutator with retrovirus and retroelement restriction activity. Sci Rep. 7, 46719. 2017.
  • A naturally occurring domestic cat APOBEC3 variant confers resistance to FIV infection. J Virol. 90, 474-85. 2016.
  • Creation of chimeric human/rabbit APOBEC1 with HIV-1 restriction and DNA mutation activities. Sci Rep. 6, 19035. 2016.
  • Helix-grafted Pleckstrin homology domains suppress HIV-1 infection of CD4-positive cells. Chembiochem. 17, 1945-1950. 2016.
  • Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity. PLoS Genet. 10, e1004761. 2014.
  • The local dinucleotide preference of APOBEC3G can be altered from 5’-CC to 5’-TC by a single amino acid substitution. J Mol Biol. 425, 4442-54. 2013.
  • GANP interacts with APOBEC3G and facilitates its encapsidation into the virions to reduce HIV-1 infectivity. J Immunol. 15, 6030-9. 2013.
  • Characterization of the ptr5+ gene involved in nuclear mRNA export in fission Yeast. Biochem Biophys Res Commun. 418, 62-6. 2012.
  • Intrinsic restriction activity by apolipoprotein B mRNA editing enzyme APOBEC1 against the mobility of autonomous retrotransposons. Nucleic Acids Res. 39, 5538-54. 2011.
  • The anti-retroviral potency of APOBEC1 deaminase from small animal species. Nucleic Acids Res. 36, 6859-6871. 2008.
  • Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis. 195, 716-25. 2007.

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