A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity

Tsujino S#, Tsuda M#, Ito J#, Deguchi S# (#equal contribution), Taha TY, Nasser H, Wang L, Rosecrans J, Suzuki R, Suzuki S, Yoshimatsu K, Ott M, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Ikeda T, Takayama K, Sato K, Tanaka S*, Tamura T*, Fukuhara T* (*correspondence). A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity. Nat Commun, 2025.